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董宇航

作者:  发布日期:2023-03-28

董宇航

化学生物学系,师资博士后

邮箱:yuhang.dong2022@mail.buct.edu.cn


教育经历:

20139-20177月   天津大学   学士

20179-20227月   天津大学   博士


工作经历:

2022-至今   北京化工大学   师资博士后


研究方向:

核酸化学及核酸功能材料的开发与医学应用,主要包括:新型核酸药物递送系统的开发、抗病毒核酸纳米药物的创制、非天然核酸药物化学与疾病治疗的应用。研究成果在国内外期刊上发表论文20余篇,包括Angew. Chem. Int. Ed.Chem. Rev.Acc. Mater. Res.Adv. Funct. Mater.Biosens. Bioelectron.iScienceACS Appl. Mater. Interfaces等。


主持项目情况:

1. 国家自然科学基金青年项目,2024-2026年,项目负责人

2. 中国博士后科学基金面上项目,2023-2024年,项目负责人

3. 中央高校基本科研业务费项目,2023-2024年,项目负责人


代表性论文:

1. Yuhang Dong+, Feng Li+, Zhaoyue Lv, Shuai Li, Meihe Yuan, Nachuan Song, Jinqiao Liu, Dayong Yang*. Lysosome Interference Enabled by Proton-Driven Dynamic Assembly of DNA Nanoframework inside Cells. Angew. Chem. Int. Ed., 2022, 61, 36, e202207770.

2. Yuhang Dong+, Yunhua Guo+, Wenzhe Song+, Guangjun Nie*, Feng Li*. Functional Integration of DNA and Peptide-Based Supramolecular Nanoassemblies for Cancer Therapy. Acc. Mater. Res., 2023, 4, 10, 892-905.

3. Yuhang Dong+, Chi Yao+, Yi Zhu, Lu Yang, Dan Luo, Dayong Yang*. DNA Functional Materials Assembled from Branched DNA: Design, Synthesis and Applications. Chem. Rev., 2020, 120, 17, 9420-9481. (ESI top1%)

4. Meihe Yuan+, Yuhang Dong+, Zhaoyue Lv+, Jinqiao Liu, Mingxing Liu, Mengdi Xu, Xiaocui Guo*, Chi Yao*, Dayong Yang*. Controlled Sequential Assembly of DNA Nanoparticles Inside Cells Enabling Mitochondrial Interference. Adv. Funct. Mater., 2023, DOI: 10.1002/adfm.202312880.

5. Jinqiao Liu+, Yuhang Dong+, Jianpu Tang, Junlin Wu, Yan Huang, Chi Yao*, Dayong Yang*. A DNA Nanocomplex with Bifunctions of Reactive Oxygen Species Scavenging and Gene Silencing for Synergistic Repair of Myocardial Infarction. Nano Today, 2024, 55, 102185.

6. Yuhang Dong+, Chi Yao+, Zhi Wang, Dan Luo, Dayong Yang*. Target-triggered polymerization of branched DNA enables enzyme-free and fast discrimination of single-base changes. iScience, 2019, 21, 228-240.