Zhuo Wang
Professor
College of Chemistry
Email:wangzhuo77@buct.edu.cn
Office: Room 402, Zonghe Building
Lab: Room 209B, Huaxin Building
Research Interests
Organic Chemistry & Chemical Biology — Functional Organic Molecule Synthesis, Bioanalysis and Sensing.
Design and synthesis of molecular probes for bioanalysis and imaging
Design and synthesize organic molecules with good photostability for the detection of active substances in organisms, high-resolution imaging of organelles, and analysis of biosensor arrays.
Design and construct the molecular-nano assembly platform for disease diagnosis and treatment
Functional organic molecules with specific recognition and photoactivity are assembled with nanostructures to construct composite systems for the diagnosis and treatment of diseases.
Development of composite antibacterial materials
Design and synthesis of organic-inorganic composite antibacterial materials with good biocompatibility
Biography
Education &work experience
B.S. Northeast Normal University (1996.9-2000.7)
M.S Northeast Normal University (2000.9-2003.7)
Ph.D. Chemistry of Institute, Chinese Academy of Science (2003.9-2006.7)
Postdoctor, Bowling Green State University, USA (2006.9-2008.12)
Assistant Professor, National Center for Nanoscience and Technology (2009.3-2012.3)
Associate Professor, National Center for Nanoscience and Technology (2012.3-2014.3)
Professor, National Center for Nanoscience and Technology (2014.3-2015.10)
Professor, Beijing University of Chemical Technology (2015.11-present)
Awards &hornours
Coastal Hongmeng Scholarship (2020)
First Prize of the 9th Beijing College Student Chemistry Experiment Competition (Instructor) (2017，2019)
Beijing Science and Technology Award (Second Prize) (2016)
Lu Jiaxi Young Talent Award from CAS (2012)
The Excellent Young Scientist Foundation of NSFC (2012)
The Science and Technology Award of China Association for Instrumental Analysis (2011)
Projects &Funding
Excellent Young Scientist Foundation (Grant No. 21222502), General Program, 2013.1-2015.12
National Natural Science Foundation of China (Grant No. 21575032), 2016.1-2019.12
Beijing Natural Science Foundation, General Program (Grant No. L172018), 2017.10-2019.6
National Natural Science Foundation of China (Grant No. 21775010), 2018.1-2021.12
National Natural Science Foundation of China (Grant No. 81961138011)，2020.1-2022.12
Academy of Medical Sciences Newton Advanced Fellowship (Grant No. ZK20210041), 2021.3-2023.2
National Key Research and Development Program of China(Grant No. 2021YFC2101500), 2021.7-2024.6
Beijing Natural Science Foundation, General Program (Grant No. 7232342), ￥20,0000, 2023.1-2025.12
Publications
1.Yujie Geng, Zhuo Wang*, Jiaying Zhou, Mingguang Zhu, Jiang Liu, Tony D. James*, Recent progress in the development of fluorescent probes for imaging pathological oxidative stress, Chem. Soc. Rev. 2023, 52, 3873-3926.
2.Lijun Ma, Yujie Geng, Guoyang Zhang, Ziwei Hu, Tony D. James*, Xuefei Wang*, Zhuo Wang*, Near-infrared bodipy based molecular rotors for β-amyloid imaging in vivo, Adv. Health Mater. 2023, 230073.
3.Yujie Geng, Hanchen Zhang, Guoyang Zhang, Jiaying Zhou, Mingguang Zhu, Lijun Ma, Xuefei Wang*, Tony D. James*, Zhuo Wang*, Near-infrared fluorescent probe for the insitu visualization of oxidative stress in the brains of neuroinflammatory and schizophrenic mice, Anal. Chem. 2023, 95, 11943-11952.
4.Jiguang Li, Guoyong Pan, Grigory V. Zyryanov, Yanghan Peng, Guoyang Zhang, Lijun Ma, Shuo Li, Peiyu Chen, Zhuo Wang*, Positively charged semiconductor conjugated polymer nanomaterials with photothermal activity for antibacterial and antibiofilm activities in vitro and in vivo, ACS Appl. Mater. Interfaces. 2023, 15, 40864-40876.
5.Shuo Li, Guoyang Zhang, Yanghan Peng, Peiyu Chen, Jiguang Li, Xuefei Wang*, Zhuo Wang*, Tyrosinase-activated nanocomposites for double-modals imaging guided photodynamic and photothermal synergistic therapy, Adv. Health. Mater. 2023, 12, 2300327.
6.Shuo Li, Yuzhi Chen, Peinan He, Yufan Ma, Yajie Cai, Xinhui Hou, Guoyang Zhang, Xin Zhang*, Zhuo Wang*, Aggregation-induced emission (AIE) photosensitizer combined polydopamine nanomaterials for organelle-targeting photodynamic and photothermal therapy by the recognition of sialic acid, Adv. Health. Mater. 2022, 11, 2200242.
7.Lijun Ma, Yajie Cai, Shuo Li, Jiguang Li, Peiyu Chen, Grigory V. Zyryanov, Dmitry S. Kopchuk, Igor S. Kovalev, Zhuo Wang*, New degradable semiconducting polymers for photoacoustic imaging of λ carrageenan-induced arthritis mouse model, Anal, Chem. 2022, 94, 14322−14330.
8.Yujie Geng, Guoyang Zhang, Yuzhi Chen, Yanghan Peng, Xuefei Wang*, Zhuo Wang*，Si-Rhodamine derivatives for brain fluorescence imaging and monitoring of H2S in the brain of schizophrenic mice before and after treatment, Anal. Chem. 2022, 94, 1813-1822.
9.Yawen Li, Zitong Liu, Yufan Ma, Yuzhi Chen, Kun Ma, Xuefei Wang, Deqing Zhang, Zhuo Wang*, Semiconducting nanocomposite with AIEgen-triggered enhanced photoluminescence and photodegradation for dual-modality tumor imaging and therapy, Adv. Funct. Mater. 2019, 29, 1903733.
10.Yuzhi Chen, Wenting Ai, Xuan Guo, Yawen Li, Yufan Ma, Lifang Chen, Hui Zhang, Tongxin Wang*, Xin Zhang*, and Zhuo Wang*, Mitochondria-targeted polydopamine nanocomposite with AIE photosensitizer for image-guided photodynamic and photothermal tumor ablation, Small, 2019, 15, 1902352.
links：
Research Group:https://www.x-mol.com/groups/wang_zhuo