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梁瑞政

作者：  发布日期：2023-02-23

❖ 基本信息：

男；教授，博士生导师；国家优青

在读研究生：博士研究生2名，硕士研究生7名

电子邮箱：liangrz@mail.buct.edu.cn

实验室楼名及房间号：无机楼222

课题组网站：https://www.x-mol.com/groups/liang_rz


❖ 教育经历：

2005.09-2009.07： 广西大学，应用化学，学士

2009.09-2015.07： 北京化工大学，化学，博士(导师：段雪院士)

2014.02-2014.08： 英国牛津大学，化学，博士联合培养(国家留学基金委资助)


❖ 工作经历：

2015.07-2019.03：北京化工大学理学院，副教授(人才引进)

2019.04-2020.12:  北京化工大学化学学院，副教授

2021.01至今：北京化工大学化学学院，教授


❖ 学术荣誉：

  1. 国家自然科学基金和北京市自然科学基金评审专家，科技部111引智基地评审专家

  2. Exploration、Chin. Chem. Lett.、Acta Phys-chim Sin青年编委，Appl. Sci.编委，Front. Mol. Biosci.客座主编

  3. Nat. Commun.、J. Am. Chem. Soc、Adv. Mater.、ACS Nano、Adv. Sci.等30余期刊审稿人/仲裁人

  4. 中国化学学会高级会员，中国化工学会会员，精细化工青年委员会委员


❖ 主要研究领域：

  1. 生物医用材料

  2. 抗肿瘤纳米体系及诊疗一体化

  3. 骨修复和骨填充生物活性材料


❖ 主要承担项目：

  1. 国家自然科学基金优秀青年项目，2024.01-2026.12，主持

  2. 国家自然科学基金面上项目，2020.01-2023.12，主持

  3. 国家自然科学基金青年项目，2017.01-2019.12，主持

  4. 北京市自然科学基金面上项目，2021.01-2023.12，主持

  5. 北京市自然科学基金青年项目，2017.01-2018.01，主持

  6. 华熙生物科技股份有限公司科技专项，2022.01-2024.12，主持

  7. 国家自然科学基金基础科学中心项目，2023.01-2027.12，参与

  8. 国家973重大研发计划，2016.01-2018.12，参与

  9. 科技部111引智计划，2019.01-2023.12，项目联系人


❖ 研究成果：

致力于层状双金属氢氧化物(LDHs)生物医学复合材料的基础和应用基础研究，以第一作者或通讯作者在Nat. Commun. (2)、Adv. Mater. (5)、Chem. Soc. Rev.、ACS Nano、Adv. Funct. Mater.、Adv. Sci.、Sci. Bull.等刊物发表SCI论文60余篇。8篇论文入选ESI高被引TOP 1%论文，2篇入选热点论文。研究工作被各类学术网站亮点报道30余次。受邀担任Exploration、中国化学快报，物理化学学报青年编委，Applied Sciences编委，Frontiers in Molecular Biosciences客座主编。参编中英文专著各1部。申请国家发明专利18件，获得授权14件。荣获北京市科技进步二等奖，北京化工大学青年英才百人计划（首批）等荣誉。


❖ 代表性论文：

  1. T. Hu, Z. Gu, G. R. Williams, M. Strimaite, J. Zha, Z. Zhou, X. Zhang,* C. Tan,* R. Liang,* Layered double hydroxide-based nanomaterials for biomedical applications, Chem. Soc. Rev., 2022, 51, 6126−6176.

  2. W. Shen,# T. Hu,# X. Liu, J. Zha, F. Meng, Z. Wu, Z. Cui, Y. Yang, H. Li, Q. Zhang, L. Gu, R. Liang,* C. Tan,* Defect Engineering of Layered Double Hydroxide Nanosheets as Inorganic Photosensitizers for NIR-III Photodynamic Cancer Therapy, Nat. Commun., 2022, 13, 3384.

  3. R. Gao,# X. Mei,# D. Yan,* R. Liang,* M. Wei, Nano-photosensitizer based on layered double hydroxide and isophthalic acid for singlet oxygenation and photodynamic therapy, Nat. Commun., 2018, 9, 2798.

  4. T. Hu,# W. Shen,# F. Meng,# S. Yang, S. Yu, H. Li, Q. Zhang, L. Gu,* C. Tan,* R. Liang,* Boosting the sonodynamic cancer therapy performance of 2D layered double hydroxide nanosheet-based sonosensitizers via crystalline-to-amorphous phase transformation, Adv. Mater., 2023, 35, 2209692.

  5. Y. Yang,# T. Hu,# Y. Bian,# F. Meng, S. Yu, H. Li, Q. Zhang, L. Gu, X. Weng,* C. Tan,* R. Liang,* Coupling probiotics with 2D CoCuMo-LDH nanosheets as tumor microenvironment-responsive platform for precise NIR-II photodynamic therapy, Adv. Mater., 2023, 35, 2211205.

  6. Z. Lv,# T. Hu,# Y. Bian,# G. Wang, Z. Wu, H. Li, X. Liu, S. Yang, C. Tan,* R. Liang,* X. Weng*, A MgFe-LDH Nanosheet-Incorporated Smart Thermo-Responsive Hydrogel with Controllable Growth Factor Releasing Capability for Bone Regeneration, Adv. Mater., 2023, 35, 2206545.

  7. W. Liu, S. Xu, S. Guan, R. Liang,* M. Wei,* D. G. Evans, X. Duan, Confined synthesis of carbon nitride in a layered host matrix with unprecedented solid-state quantum yield and stability, Adv. Mater., 2018, 30, 1704376.

  8. L. Peng, X. Mei, J. He, J. Xu, W. Zhang,* R. Liang,* M. Wei,* D. G. Evans, X. Duan, Monolayer Nanosheets with an Extremely High Drug Loading toward Controlled Delivery and Cancer Theranostics, Adv. Mater., 2018, 30, 1707389.

  9. T. Hu, X. Mei, Y. Wang, X. Weng,* R. Liang,* M. Wei,* Two-Dimensional Nanomaterials: Fascinating Materials in Biomedical Field,Sci. Bull., 2019, 64, 1707−1727.

  10. R. Liang, R. Tian, L. Ma, L. Zhang, Y. Hu, J. Wang, M. Wei,* D. Yan,* D. G. Evans, X. Duan, A Supermolecular Photosensitizer with Excellent Anticancer Performance in Photodynamic Therapy, Adv. Funct. Mater., 2014, 24, 3144−3151.

  11. R. Liang, S. Xu, D. Yan, W. Shi, R. Tian, H. Yan, M. Wei,* D. G. Evans, X. Duan, CdTe Quantum Dots/Layered Double Hydroxide Ultrathin Films with Multicolor Light Emission via Layer-by-Layer Assembly, Adv. Funct. Mater., 2012, 22, 4940−4948.

  12. Y. Wang,# S. Shen,# T. Hu, G. R. Williams, Y. Bian, B. Feng, R. Liang,* X. Weng,* Layered Double Hydroxide Modified Bone Cement Promoting Osseointegration via Multiple Osteogenic Signal Pathways, ACS Nano, 2021, 15, 9732−9745.

  13. G. Wang,# Z. Lv,# T. Wang,# T. Hu, Y. Bian, Y. Yang, R. Liang,* C. Tan,* X. Weng,* Surface Functionalization of Hydroxyapatite Scaffolds with MgAlEu-LDH Nanosheets for High-Performance Bone Regeneration, Adv. Sci., 2023, 10, 2204234.

  14. Y. Bian, X. Cai, Z. Lv, Y. Xu, H. Wang, C. Tan,* R. Liang,* X. Weng,* Layered Double Hydroxides: A Novel Promising 2D Nanomaterial for Bone Diseases Treatment, Adv. Sci., 2023, 10, 2301806.

  15. Y. Zhu#, Y. Wang#, G. R. Williams, L. Fu, J. Wu, H. Wang, R. Liang,* X. Weng,* M. Wei,* Multicomponent Transition Metal Dichalcogenide Nanosheets for Imaging-Guided Photothermal and Chemodynamic Therapy, Adv. Sci., 2020, 7, 2000272. (Front Cover)

  16. S. Wang,# S. Yang,# Z. Cui, X. Liu, Y. Yang, T. Wang, W. Ma, Y. Zhou, R. Liang,* D. Yan,* H. Chen,* In-situ Activation of CuAl-LDH Nanosheets to Catalyze Bioorthogonal Chemistry in vivo in Tumor Microenvironment for Precise Chemotherapy and Chemodynamic Therapy, Chem. Eng. J., 2023, 457, 141186.

  17. S. Wang, T. Hu, G. Wang, Z. Wang, D. Yan*, R. Liang,* C. Tan,* Ultrathin CuFe2S3 nanosheets derived from CuFe-layered double hydroxide as an efficient nanoagent for synergistic chemodynamic and NIR-II photothermal therapy, Chem. Eng. J., 2021, 419, 129458.

  18. J. Wu, G. R. Williams, Y. Zhu, T. Hu, H. Wang, W. Zhao, R. Liang,* X. Weng,* M. Wei,* Ultrathin Chalcogenide Nanosheets for Photoacoustic Imaging-Guided Synergistic Photothermal/Gas Therapy, Biomaterials, 2021,273, 120807.

  19. X. Mei#, T. Hu#, H. Wang, R. Liang,* W. Bu,* M. Wei,* Highly dispersed Nano-enzyme Triggered Intracellular Catalytic Reaction toward Cancer Specific Therapy,Biomaterials, 2020, 258, 120257.

  20. X. Mei, W. Wang, L. Yan, T. Hu, R. Liang,* D. Yan,* M. Wei,* David G. Evans, Xue Duan, Hydrotalcite Monolayer toward High Performance Synergistic Dual-modal Imaging and Cancer Therapy, Biomaterials, 2018, 165, 14−24.

  21. T. Hu,# Q. Liu,# Z. Zhou,# W. Zhao, H. Huang, F. Meng, W. Liu, Q. Zhang, L. Gu, R. Liang,* C. Tan,* Preparation of Dye Molecule-Intercalated MoO3 Organic/Inorganic Superlattice Nanoparticles for Fluorescence Imaging-Guided Catalytic Therapy,Small, 2022, 18, 2200595.

  22. T. Hu, Z. Wang, W. Shen, R. Liang,* D. Yan,* M. Wei,* Recent advances in innovative strategies for enhanced cancer photodynamic therapy, Theranostics, 2021, 11, 3278−3300.

  23. T. Hu, B. Xue, F. Meng, L. Ma, Y. Du, S. Yu, R. Ye, H. Li, Q. Zhang, L. Gu, Z. Zhou,* R. Liang,* C. Tan,* Preparation of 2D polyaniline/MoO3-x superlattice nanosheets via intercalation-induced morphological transformation for efficient chemodynamic therapy, Adv. Healthcare Mater., 2023, 2202911.

  24. W. Liu, S. Xu, Z. Li, R. Liang,* M. Wei,* D. G. Evans, X. Duan, Layer-by-Layer Assembly of Carbon Dots-Based Ultrathin Films with Excellent Quantum Yield and Temperature Sensing Performance, Chem. Mater., 2016, 28, 5426−5431.

  25. R. Liang, D. Yan, R. Tian, X. Yu, W. Shi, C. Li, M. Wei*, D. G. Evans, X. Duan, Quantum Dots-Based Flexible Films and Their Application as the Phosphor in White Light-Emitting Diodes, Chem. Mater., 2014, 26, 2595−2600.

  26. J. Wu#, S. Zhang#, X. Mei, N. Liu, T. Hu, R. Liang,* D. Yan,* M. Wei,* Ultrathin Transition Metal Chalcogenide Nanosheets Synthesized via Topotactic Transformation for Effective Cancer Theranostics, ACS Appl. Mater. Interfaces, 2020, 12, 48310−48320.

  27. X. Mei, S. Xu, T. Hu, L. Peng, R. Gao, R. Liang,* M. Wei,* D. G. Evans, X. Duan, Layered double hydroxide monolayers for controlled loading and targeted delivery of anticancer drugs, Nano Res., 2018, 11, 195–205.

  28. T. Hu#, L. Yan#, Z. Wang, W. Shen, R. Liang,* D. Yan,* M. Wei,* A pH-responsive Ultrathin Cu-based Nanoplatform for Specific Photothermal and Chemodynamic Synergistic Therapy,Chem. Sci., 2021, 12, 2594–2603.

  29. X. Mei, J. Ma, X. Bai, X. Zhang, S. Zhang, R. Liang,* M. Wei,* D. G. Evans, X. Duan, A bottom-up synthesis of rare-earth-hydrotalcite monolayer nanosheets toward multimode imaging and synergetic therapy, Chem. Sci., 2018, 9, 5630−5639.

  30. R. Liang, S. You, L. Ma, C. Li, L. Zhang, M. Wei*, D. Yan*, M. Yin*, W. Yang, D. G. Evans, X. Duan, A Supramolecular Nanovehicle toward Systematic and Targeted Cancer Therapy, Chem. Sci., 2015, 6, 5511−5518.


❖ 获奖情况：

本人荣获北京市科技进步二等奖；北京化工大学“青年英才百人计划” B类；“唐敖庆奖学金”；北京化工大学“校长奖学金”；北京化工大学“博士攀登计划奖学金”；北京化工大学博士研究生“国家奖学金”。

培养/协助培养研究生有3人荣获北京化工大学“校长奖学金”，4人荣获“唐敖庆奖学金”，10余人次荣获国家奖学金。


❖ 招生专业：

化学、化工、材料等相关专业

❖ 招生要求：

态度端正，有责任心，踏实努力，富有团队精神，勤于思考，勇于创新。



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